Difference between revisions of "Sensing Barcelona 2019"

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[[File:Sensingbarcelona.PNG|100px|thumb|right|Logo of Sensing Barcelona]]
  
 
== Sensing Barcelona 2019 ==
 
== Sensing Barcelona 2019 ==
 
 
Sensing Barcelona is a team from the Polytechnic University of Catalonia (UPC) and the University of Vic - Central University of Catalonia (UVic-UCC) competing in the SensUs 2019 event. For SensUs 2019, Sensing Barcelona investigated the possibilities for creating a biosensor which is able to measure the concentration of [[Adalimumab]]. The full TRD can be found [https://digital2019.sensus.org/storage/527/Sensing-Barcelona-(Spain)---Team-Results-Document.pdf via this link]
 
Sensing Barcelona is a team from the Polytechnic University of Catalonia (UPC) and the University of Vic - Central University of Catalonia (UVic-UCC) competing in the SensUs 2019 event. For SensUs 2019, Sensing Barcelona investigated the possibilities for creating a biosensor which is able to measure the concentration of [[Adalimumab]]. The full TRD can be found [https://digital2019.sensus.org/storage/527/Sensing-Barcelona-(Spain)---Team-Results-Document.pdf via this link]
  
 
== Method ==
 
== Method ==
 
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Lateral Flow immunoassay
Fluorescence
 
  
 
==Molecular Recognition ==
 
==Molecular Recognition ==
 
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[[Adalimumab]] bonds to the antibody TNF-α.
NHS ester labeling, this is done using click chemistry.
 
  
 
== Physical Transduction ==
 
== Physical Transduction ==
 
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Benefiting from the  chemical and  pigment properties of the  colloidal  gold  molecule, characterized  by  its  reddish  colour,  the  device  detects  the intensity of  the  sample  through image acquisition and associates it with a certain concentration. In other words, the intensity of the pigment is directly proportional to the amount of Adalimumab.
Fluorescence within a certain part of the EM spectrum occurs. The intensity is measured using a spectrophotometer.
 
 
 
== Cartridge ==
 
 
 
Fluid handling can be done with only a pipette and the cuvette and the user need only insert the cuvette into the device in order to take a measurement.
 
  
 
== Reader Instrument ==
 
== Reader Instrument ==
 
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85.06x56.21 mm touchscreen.
The user interface is compromised primarily of the integrated touch screen.
 

Latest revision as of 00:16, 13 September 2020

Logo of Sensing Barcelona

Sensing Barcelona 2019

Sensing Barcelona is a team from the Polytechnic University of Catalonia (UPC) and the University of Vic - Central University of Catalonia (UVic-UCC) competing in the SensUs 2019 event. For SensUs 2019, Sensing Barcelona investigated the possibilities for creating a biosensor which is able to measure the concentration of Adalimumab. The full TRD can be found via this link

Method

Lateral Flow immunoassay

Molecular Recognition

Adalimumab bonds to the antibody TNF-α.

Physical Transduction

Benefiting from the chemical and pigment properties of the colloidal gold molecule, characterized by its reddish colour, the device detects the intensity of the sample through image acquisition and associates it with a certain concentration. In other words, the intensity of the pigment is directly proportional to the amount of Adalimumab.

Reader Instrument

85.06x56.21 mm touchscreen.