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Traumatic Brain Injury

322 bytes added, 21:32, 7 December 2022
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Other ways for diagnosing TBI can include various imaging tests like a CT scan or an MRI scan. However, these imaging techniques are often not sensitive/specific enough for milder TBI. According to experts, only 5-10% of mild TBI patients have abnormal CT/MRI scans. The problem with these scans is that they can only detect damage on a macroscopic level, whereas mild TBI manifests primarily at a microscopic level. Therefore, doctors can mistakenly believe that patients with a standard CT or MRI scan have not suffered a TBI.<ref name="Arti28">McKinlay, A., Lin, A., & Than, M. (2018). A comparison of emergency department medical records to parental self-reporting of traumatic brain injury symptoms. Concussion, 3(1), CNC52. https://doi.org/10.2217/cnc-2017-0017</ref> All in all, improvements are needed to objectively and effectively determine whether or not a patient is suffering from a TBI.
 
== State of the Art ==
Currently, the concentration of GFAP is typically measured in blood plasma (liquid component of blood in which blood cells are absent) or serum (plasma from which the clotting proteins have been removed). Classic methods for the detection of GFAP include ELISA (Enzyme-Linked Immunosorbent Assay).