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Sandbox

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== Team Sandbox 2019 2018 ==
For Sensus 20192018, Team Sandbox investigated the possibilities for creating a biosensor which is able to measure the concentration of adalimumab[[Vancomycin]].The full TRD can be found [https://digital.sensus.org/storage/264/Team-Results-Document---AUC.pdf via this link]
== Method ==
 
Spectrophotometry (Light absorbtion). Vanomycin has the property that it absorbs photons of a specific wavelength, the strength of the absorbtion is the dependant on the concentration. By looking at the transmission for a specific wavelenght of light the concentration of Vanomycin can be determined.
 
==Molecular Recognition ==
 
The detection method is based on the absorbance properties that vancomycin possesses.
 
== Physical Transduction ==
 
UV light (280 nm) was immited on a quartz cuvette. The light that is not absorbed passes through an optical filter (bandpass filter with center wavelength 300 nm) which then falls on a sicilone detector.
 
== Cartridge ==
 
To plasma spiked with vancomycin, trichloroacetic acid (TCA) is added. The mixture is then centrifuged at 15000 rpm for 3 mins to separated proteins from plasma. Then, the supernatant is seperated from the precipitated proteins, and diluted to 1:10 volume ratio.
 
== Reader Instrument ==
 
No information is given
 
 
== Prizes if won ==
 
Public Inspiation Award

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