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== VancoSense 2018 == VancoSense is a team competing in Sensus 2018, its university is the KU Leuven. For Sensus..."
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== VancoSense 2018 ==
VancoSense is a team competing in Sensus 2018, its university is the KU Leuven. For Sensus 2018, VancoSense investigated the possibilities for creating a biosensor which is able to measure the concentration of [[Vancomycin]]. The full TRD can be found [https://digital.sensus.org/storage/254/Team-Results-Document---VancoSense.pdf via this link]
== Method ==
Electrochemical impedance spectroscopy
==Molecular Recognition ==
The vancomyocin is bound by its own reaction against D-ala-D-ala motif in a peptide that is bound to a carbon nanotube, which in turn is bound to the electrode surface.
== Physical Transduction ==
The concentration of vancomyocin is measured in the biosensor at a constant temperature of 37 degrees. The concentration is measured by applying a specific voltage and measuring the resulting current from which the concentration can be calculated using a specific oxidation potential measured previously in the lab.
== Cartridge ==
The sample is first mixed with an equal volume of methanol, which releases the vancomyocin bound by HSA. After this the sample is diluted with 3 volumes of PBS, reaching a dilution of 1/5. A 30 ul v drop is then pipetted onto the cartrige, which is then placed in the biosenor.
== Reader Instrument ==
The user interacts with the device using a touchscreen, which displays the output of the device. The user can also start and stop measurements with the touchscreen and export data.
Translational Potential award
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