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VancoSense 2018

1,575 bytes added, 14:36, 28 July 2020
Created page with "200px|thumb|right|Logo of Team Sanbox == VancoSense 2018 == VancoSense is a team competing in Sensus 2018, its university is the KU Leuven. For Sensus..."
[[File:sandbox.jpg|200px|thumb|right|Logo of Team Sanbox]]


== VancoSense 2018 ==

VancoSense is a team competing in Sensus 2018, its university is the KU Leuven. For Sensus 2018, VancoSense investigated the possibilities for creating a biosensor which is able to measure the concentration of [[Vancomycin]]. The full TRD can be found [https://digital.sensus.org/storage/254/Team-Results-Document---VancoSense.pdf via this link]

== Method ==

Electrochemical impedance spectroscopy

==Molecular Recognition ==

The vancomyocin is bound by its own reaction against D-ala-D-ala motif in a peptide that is bound to a carbon nanotube, which in turn is bound to the electrode surface.

== Physical Transduction ==

The concentration of vancomyocin is measured in the biosensor at a constant temperature of 37 degrees. The concentration is measured by applying a specific voltage and measuring the resulting current from which the concentration can be calculated using a specific oxidation potential measured previously in the lab.

== Cartridge ==

The sample is first mixed with an equal volume of methanol, which releases the vancomyocin bound by HSA. After this the sample is diluted with 3 volumes of PBS, reaching a dilution of 1/5. A 30 ul v drop is then pipetted onto the cartrige, which is then placed in the biosenor.

== Reader Instrument ==

The user interacts with the device using a touchscreen, which displays the output of the device. The user can also start and stop measurements with the touchscreen and export data.

== Prizes==

Translational Potential award